The Zhang Group

Group News

Congrats Hong-Xiu Xiao and Haoxiang Wei! Our collaborative work with Prof.Xian-Wen Yang at Third Institute of Oceanography, Ministry of Natural Resources and Prof. Ping Wang at Shanghai University of Traditional Chinese Medicine "Lead Optimization of Butyrolactone I as an Orally Bioavailable Antiallergic Agent Targeting FcγRIIB" was accepted by [J. Med. Chem.] as an article. (Apr. 19, 2024) Congrats Yujie Niu, Minggui Lin, Hao Cui, and Yang Shen! Our paper "Synthetic Studies toward Pseudolaric Acids: Radical Cyclization to Form Bridged Scaffold" was accepted by [CJC] as a concise report. (Mar. 19, 2024) Congrats Pengfei Fu, Tao Liu, and Yang Shen! Our paper "Divergent Total Syntheses of Illicium Sesquiterpenes through Late-Stage Skeletal Reorganization" was accepted by [JACS] as an article. (Aug. 10, 2023) Congrats Hao Cui and Yang Shen! Our account "Synthesis of Clionastatins A and B through Enhancement of Chlorination and Oxidation Levels of Testosterone" was accepted by [CJC]. (Aug. 11, 2022) Congrats Hao Cui and Yang Shen! Our work "Two-Stage Syntheses of Clionastatins A and B" was accepted by [JACS]. (May 16, 2022) Congrats Renzhi Chen, Dongsheng Qiu and Xin Lei! Our work "Total Synthesis and Assignment of the Absolute Configuration of (+)-Omphalic Acid" was accepted by [Org Lett]. (Aug. 16, 2021) Congrats Renzhi Chen, Feng Zhang, and Yuhui Hua! Our work "Total Synthesis of Stemarene and Betaerene Diterpenoids: Divergent Ring-Formation Strategy and Late-Stage C−H Functionalization" was accepted by [CCS Chem]. (Mar. 28, 2021) Congrats Yang Shen, Linbin Li, and Xiaoxia Xiao! Our work "Site-Specific Photochemical Desaturation Enables Divergent Syntheses of Illicium Sesquiterpenes" was accepted by [JACS]. (Feb. 18, 2021) Congrats Xunjin Jiang, Zhixiong Zeng, and Yuhui Hua! Our work "Merging C–H Vinylation with Switchable 6π-Electrocyclizations for Divergent Heterocycle Synthesis" was accepted by [JACS]. (Aug. 12, 2020) Congrats Xunjin Jiang! Our collaborative work with Prof. Hu of XMU Medical School "Structure-Activity Relationship Study Enables the Discovery of a Novel Berberine Analogue as RXRα Activator to Inhibit Colon Cancer" was accepted by [J. Med. Chem.]. (May. 12, 2020) Congrats Renzhi Chen, Yang Shen, and Sihan Yang! Our Minireview "Conformational Design Principles in Total Synthesis" was accepted by [Angew. Chem. Int. Ed.]. (Apr. 16, 2020) Congrats Minggui Lin, Hao Cui! Our Communication "Domino enyne metathesis en route to skeletally diverse, privileged scaffolds: synthesis of the tricyclic core of pseudolaric acid F" was accepted by [Org. Chem. Front.]. (Jun. 16, 2019) Congrats Zhixiong Zeng, Yifan Zhao! Our Communication "Divergent total syntheses of five illudalane sesquiterpenes and assignment of the absolute configuration" was accepted by [Chem. Commun.]. (Mar. 15, 2019) Congrats Renzhi Chen, Linbin Li, Na Lin, Rong Zhou, and Hejun Deng! Our Communication "Asymmetric Total Synthesis of (+)-Majusculoic Acid via a Dimerization–Dedimerization Strategy and Absolute Configuration Assignment" was accepted by [Org. Lett.]. (Feb. 15, 2018) Congrats Zhixiong Zeng, Cheng Chen! Our work "Enantioselective Total Synthesis of Periconiasin A" was accepted by [Org. Chem. Front.]. (Dec. 1, 2017) Congrats Minggui Lin, Zhixiong Zeng, Na Lin, Yang Shen, Bin Tang, Fan Li, and Chen Chen! Our work "Conformational Bias by a Removable Silyl Group: Construction of Bicyclo[n.3.1]alkenes via Ring Closing Metathesis" was accepted by [Chem. Eur. J.]. (Nov. 9, 2017) Congrats Chenguang Liu, Renzhi Chen, Yang Shen, and Zhanhao Liang! Our work "Total Synthesis of Aplydactone via a Conformationally Controlled C-H Functionalization" was accepted by [Angew. Chem.]. (May 3, 2017) Congrats Chenguang Liu, Zhixiong Zeng, Renzhi Chen, Xunjin Jiang, Yinglu Wang! Their work "Total Synthesis of (+)-Fusarisetin A Driven by a One-Pot Four-Reaction Process" was accepted by [Org. Lett.]. (Jan. 27, 2016) Congrats Yang Shen, Linbin Li, Zhisheng Pan, Yinglu Wang, Jundong Li, Kuangyu Wang, Xiance Wang! Their work "Protecting-Group-Free Total Synthesis of (−)-Jiadifenolide: Development of a [4 + 1] Annulation toward Multisubstituted Tetrahydrofurans" was accepted by [Org. Lett.]. (Oct. 29, 2015) Congrats Jundong Li, Huaibo Zhao, Xunjin Jiang, Xiance Wang, Haiming Hu, Lei Yu! Their work "[3+2] Cycloaddition of Azomethine Ylides:A Five-Step Synthesis of (±)-Isoretronecanol" was accepted by [Angew. Chem.]. (Mar. 28, 2015)

Dr. Yandong Zhang （张延东）
	Professor Department of Chemistry Office: 622 Lu Jiaxi Hall Labs: 621&625 Lu Jiaxi Hall Xiamen, Fujian 361005 Tel: +86-592-2181902 Email: ydzhang@xmu.edu.cn
Education Background: Postdoc, Columbia University, 2008-2010 (With Prof. Samuel J. Danishefsky) Ph.D. Peking University, 2004-2008 (With Prof. Zhen Yang) B. E. Beijing Institute of Technology, 1994-1998 (With Prof. Yingyan Jiang)
Research Interestes: Total Synthesis of natural products of significant biological activities; chemical biology based on small molecule-protein interaction.